Muva nje, inkampani edumile yensangu yezokwelapha i-Little Green Pharma Ltd ikhiphe imiphumela yokuhlaziya yezinyanga eziyi-12 yohlelo lwayo lwesilingo lwe-QUEST. Okutholakele kuyaqhubeka nokubonisa ukuthuthuka okunenjongo emtholampilo kuyo yonke ikhwalithi yokuphila ehlobene nempilo yeziguli (HRQL), amazinga okukhathala, nokulala. Ukwengeza, iziguli ezitholwe zinalezi zimo zibonise ukuthuthuka okuphawulekayo emtholampilo ekukhathazekeni, ukucindezeleka, ukuphazamiseka kokulala, nobuhlungu.
Uhlelo lwesivivinyo oluwine umklomelo lwe-QUEST, oluxhaswe ngabakwa-Little Green Pharma Ltd (LGP), lungolunye lwezifundo zomtholampilo zesikhathi eside ezinkulu emhlabeni jikelele, oluphenya umthelela wensangu yezokwelapha kukhwalithi yempilo yeziguli. Iholwa yiNyuvesi yaseSydney e-Australia, i-LGP ihlinzeke ngokukhethekile ababambiqhaza ngamafutha ensangu enziwe e-Australia anesaphulelo. Le mithi ye-cannabis iqukethe izilinganiso ezihlukene zezithako ezisebenzayo, nakuba iziguli eziningi zasebenzisa ukwakheka kwe-CBD kuphela ukugcina ukufaneleka kokushayela ngesikhathi socwaningo.
Ucwaningo luphinde lwathola ukwesekwa kumshwalense wezempilo ozimele ongenzi nzuzo i-HIF Australia, isiqondiso esivela kuphaneli yabeluleki abanolwazi, kanye nokugunyazwa okuvela ezinhlanganweni zikazwelonke ezifana ne-MS Research Australia, Chronic Pain Australia, Arthritis Australia, ne-Epilepsy Australia. Imiphumela yezinyanga eziyi-12 yohlelo lwesivivinyo lwe-QUEST iye yabuyekezwa kontanga futhi yashicilelwa kujenali yokufinyelela okuvulekile i-PLOS One.
Uhlolojikelele Lwesivivinyo
Phakathi kukaNovemba 2020 noDisemba 2021, uhlelo lwe-QUEST lwamema iziguli zase-Australia ezisanda kuthola insangu yezokwelapha futhi ezihlushwa yizimo ezingamahlalakhona ezinjengobuhlungu, ukukhathala, ukuphazamiseka kokulala, ukudangala nokukhathazeka ukuthi zibambe iqhaza.
Abahlanganyeli babeneminyaka esukela ku-18 kuya kwengama-97 (isilinganiso: 51), kanti u-63% kungabesifazane. Izimo ezivame ukubikwa zazibuhlungu obungapheli be-musculoskeletal kanye ne-neuropathic (63%), kulandelwa ukuphazamiseka kokulala (23%), kanye nokukhathazeka okujwayelekile nokucindezeleka (11%). Ingxenye yabahlanganyeli yayinezinkinga eziningi.
Ingqikithi yodokotela abazimele abayi-120 kuzo zonke izifundazwe eziyisithupha baqashe ababambiqhaza. Bonke ababambiqhaza bagcwalise uhlu lwemibuzo lokuqala ngaphambi kokuqala ukwelashwa kwe-cannabis, okulandelwa yimibuzo elandelayo emasontweni amabili bese kuthi njalo ezinyangeni ezi-1-2 ezinyangeni eziyi-12. Ngokuphawulekayo, ukufaneleka kwakudinga ukwehluleka kokwelashwa kwangaphambili noma imiphumela emibi evela emithini evamile.
Imiphumela Yesivivinyo
Ukuhlaziywa kwezinyanga eziyi-12 kwembule ubufakazi obunamandla kakhulu (p<0.001) bentuthuko ku-HRQL iyonke, ukulala, nokukhathala phakathi kwabahlanganyeli. Ukukhululeka kwezimpawu okunenjongo ngokomtholampilo kwabonwa futhi emaqenjini amancane anokukhathazeka, ubuhlungu, ukucindezeleka, nokuphazamiseka kokulala. “Imiphumela enenjongo yomtholampilo” ibhekisela kokutholwe okuthinta kakhulu impilo yomuntu ngamunye noma inhlalakahle, okungase kuguqule ukuqonda noma izindlela zokwelashwa kochwepheshe bezempilo.
Bonke ababambiqhaza babambelela esivumelwaneni sesilingo, bephuza imishanguzo yomlomo ye-cannabis ngemuva kokwelashwa okungaphumelelanga kwangaphambili ngemithi yokwelapha ejwayelekile. Ukuhlaziywa kubonise imiphumela emihle emangalisayo yomuthi owodwa we-cannabis kulo lonke uhla olubanzi lwezimo zokuphika. Lokhu okutholwe yizinyanga eziyi-12 kuphinde kuqinisekise imiphumela yokuqala yezinyanga ezi-3 yesivivinyo se-QUEST eshicilelwe ku-PLOS One ngoSepthemba 2023.
UDkt. Paul Long, uMqondisi Wezokwelapha we-LGP, uthe: "Sizizwa sihloniphekile ngokuqhubeka nokuhola ucwaningo lwe-cannabis yezokwelapha futhi sisekele lesi sivivinyo esibalulekile emthelela waso ezingeni lempilo yeziguli. Le miphumela ibaluleke kakhulu kodokotela base-Australia, njengoba ifakazela ukusebenza kahle kwensangu yezokwelapha ekhule e-Australia ezigulini zendawo."
Wanezela: “Ngokusebenzisa imikhiqizo ekhiqizwa ekhaya futhi sihilela iziguli zendawo, sikhiqiza idatha ebaluleke kakhulu ukusiza odokotela banikeze imithi ngokuzethemba, ekugcineni sithuthukise ukunakekelwa kwesiguli ezweni lonke.Ngaphezu kwezinzuzo zezokwelapha, lolu cwaningo lunikeze ukufinyelela kubanikezeli abanolwazi kanye nemithi ethengekayo—isinyathelo esiqhubekayo ocwaningweni lwethu oluqhubekayo lwe-QUEST Global.
UDkt. Richard Norman, Umeluleki Wezomnotho Wezempilo ovivinyweni lwe-QUEST kanye noProfessor Ongumsizi e-Curtin University, uthe: "Le miphumela ibalulekile ngoba ikhombisa ukuthi insangu yezokwelapha ingaba neqhaza lesikhathi eside ekuthuthukiseni imiphumela yezempilo ezimeni ezingamahlalakhona, kunokuba isebenze njengesixazululo 'sokusizakala'. Imiphumela yomhlaba wangempela yezinyanga eziyi-12 iyathembisa, ekhombisa ukuthi i-GP ingamelana neziguli ezingapheli. Okubalulekile, izinzuzo zibonakala zingaguquki kuzo zonke izimo ezinjengobuhlungu, ukukhathazeka, nezinkinga zokulala, ezinemiphumela emihle kwezinye izici zokuphila.
U-Nikesh Hirani, oyiChief Data and Propositions Officer kwa-HIF, uthe: "Ukutshala imali ocwaningweni oluqhubekayo mayelana nezinzuzo zezempilo ezingaba khona insangu yezokwelapha kubalulekile kumalungu ethu, odokotela kanye nomphakathi wonkana. Isivivinyo seminyaka emine sibe nemiphumela ekhuthazayo, nobufakazi besayensi be-QUEST obuqokomisa umthelela wayo omuhle ezimeni eziningi eziwohlozayo - ukuthuthukiswa okuqhubekayo kwezinyanga ezingu-12."
Ubuye wengeza wathi: "Umgomo oyinhloko we-HIF ukusiza amalungu ukuthi afinyelele ekukhetheni ukunakekelwa kwezempilo okuthuthukisa izinga lempilo yawo. Idatha ikhombisa ukwanda okungama-38% kwamalungu abuyisela imishanguzo yokwelashwa kwe-cannabis, okubonisa ukuqaphela kwawo amandla ayo njengokwelapha okusebenzayo."
Mayelana ne-Little Green Pharma
I-Little Green Pharma iyinkampani yomhlaba wonke, ehlanganiswe zibheke phezulu, futhi ehlukene ngokwezindawo esebenza ekulimeni, ekukhiqizeni, ekukhiqizeni nasekusabalaliseni. Njengoba inezindawo ezimbili zokukhiqiza emhlabeni wonke, ihlinzeka ngemikhiqizo yensangu esezingeni lezokwelapha esemthethweni kanye nelebula elimhlophe. Isikhungo saso saseDenmark singesinye sezindawo zokukhiqiza insangu yezokwelapha ezinkulu kunazo zonke eYurophu ethobela i-GMP, kanti indawo yaso yaseWestern Australia iwumsebenzi ophambili wasendlini osebenza ngokukhethekile ngezinhlobo zensangu ezenziwe ngezandla.
Yonke imikhiqizo ihlangabezana namazinga okulawula nawokuhlola asethwe i-Danish Medicines Agency (MMA) kanye ne-Therapeutic Goods Administration (TGA). Ngomkhiqizo okhulayo ohlukahlukene wezilinganiso zezithako ezisebenzayo, i-Little Green Pharma inikezela ngensangu yezinga lezokwelapha e-Australia, eYurophu nasezimakethe zamazwe ngamazwe. Inkampani ibeka phambili ukufinyelela kwesiguli ezimakethe zomhlaba ezisafufusa, ukubamba iqhaza ngenkuthalo kwezemfundo, ukumela, ucwaningo lwezokwelashwa, kanye nokuthuthukiswa kohlelo lokulethwa kwezidakamizwa olusha.
Isikhathi sokuthumela: Apr-21-2025